Analysis and Characterisation
Analysis and Characterisation of Antibody Drug Conjugates
Antibody-drug conjugates are incredibly complicated molecules combining biopharmaceutical and chemical properties that can be difficult to characterise and analyse.
Bioanalytics include DAR determination, purity assessment, quantification of residual unconjugated drug, analysis of conjugation site, ADC Serum stability and ADC drug release kinetics
Assays include viability & cytotoxicity assays, binding, internalisation, bystander assay, apoptosis, cell cycle analysis, tubulin polymerisation and Pgp Assays